Premier Journal of Neuroscience

About the Premier Journal of Neuroscience (PJN)

Premier Journal of Neuroscience (PJN) is an open access, peer-reviewed, quarterly journal dedicated to expanding the understanding and application of Neuroscience. PJN fosters interdisciplinary discourse and innovation across all branches of Neuroscience. The journal aims to serve as a platform for integrating diverse scholarly perspectives on contemporary challenges in the field.

Additionally, PJN prides itself on the integrity of its stringent peer-review process. Our rigorous criteria are designed to ensure that all of the articles published in the journal are not only scientifically sound, but also that they contribute to the wider ongoing dialogue in their respective fields. Authors are encouraged to engage and enter dialogue with the global scientific community in a constructive way, sharing ideas and research openly.

Publication frequency: quarterly
Indexing: Google Scholar, Ulrichsweb and others
Archived: British Library and Portico
ISSN: 2978-0020

PJN Aims and Scope

The Premier Journal of Neuroscience is dedicated to the global advancement of research, education and the scholarly understanding of Neuroscience. It aims to promote continued developments, discussion and debate through the sharing of knowledge, ideas and good practice across all branches of Neuroscience, including:

Cellular and Molecular Neuroscience
Systems and Cognitive Neuroscience
Behavioural and Clinical Neuroscience
Computational Neuroscience
Translational Neuroscience

The PJN provides readers with critically peer-reviewed, carefully selected and edited, and up-to-date publications about advances in the field that are relevant to them.

Article types – research, reviews, editorials/perspectives and correspondence-style articles will be considered.

Submit your manuscript

Plain language infographic on genetic and environmental risks, research, and therapies in neurodegenerative diseases

The Search for Answers: Causes, Risk Factors, and Current Research in Neurodegenerative Disorders
Amita Kajrolkar
Freelance Writer, Mumbai, India
Premier Journal of Neuroscience 2025;5:100013

Fig 2 | Prevalence of neurodegenerative disorder by age group

Understanding the Silent Threat: A Review to Neurodegenerative Disorders
Amita Kajrolkar
Freelance Writer, Mumbai, India
Premier Journal of Neuroscience 2025;4:100012

Nanoparticles Crossing the Blood–Brain Barrier: A Hope for Central Nervous System Disorders
Muhammad Imran Qadir and Ayesha Altaf
Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University, Multan, Pakistan
Premier Journal of Neuroscience 2025;4:100011

Fig 3 | Simultaneous acquisition of PET and MRI images in an AD patient14

The Effect of Early Diagnosis of Alzheimer’s Disease: A Short Systematic Review
Kimia Kazemi
Faculty of Medicine, Ivane Javakhishvili Tbilisi State University, Tbilisi, Georgia
Premier Journal of Neuroscience 2025;4:100010

Graph 1 | Mean age of the AD patients is 58 years, in which the minimum age of patients is 42 and the maximum age is 88

Unraveling the Biochemical and Hematological Pathways of Cognitive Decline: A Case Study of Emerging Biomarkers Linking Type 2 Diabetes Mellitus and Alzheimer’s Disease
Khadija Batool and Ambreen Ilyas
School of Biological Sciences, University of the Punjab, Lahore, Pakistan
Premier Journal of Neuroscience 2025;4:100009

Fig 1 | The mechanisms of SCI highlight the progression from primary and secondary injuries to cell death. The diagram illustrates how primary injury triggers necrosis and inflammation, which leads to oxidative stress and ionic dysregulation. These processes contribute to excitotoxicity and ultimately result in cell death. Secondary injury exacerbates these pathways, creating a feedback loop that amplifies damage

A Comprehensive Overview of Spinal Cord Injury (SCI) Experimental Models
Modinat Olushanu
Freelance Writer, London, UK
Premier Journal of Neuroscience 2025;3:100008

Fig 2 | Influence of gut microbiota on BBB integrity in AD. Dysbiosis augments gut permeability, permitting microbial components and neurotoxic molecules to disturb BBB integrity through enhanced neuroinflammation. Adapted from Khan et al. (2020) [DOI: 10.3390/cells9040853] under CC BY 4.0 license

Gut Dysbiosis in Alzheimer’s Disease Pathogenesis and Therapeutic Implications
Iqra Nadeem
Department of Neurobiology and Anatomy, Key Laboratory of Neurobiology, Xuzhou Medical University, Xuzhou, China
Premier Journal of Neuroscience 2025;2:100007

Fig 2 | The salience network is thought to facilitate switching between the DMN and the CEN Credits: https://doi.org/10.1073/pnas.0800005105

Real-Time Brain Feedback Reveals the DMN’s Role in Creativity and Idea Formation
Giorgi Svanishvili
Depertment of Clinical Research, Anatomical Researches and Skills Centre, Tbilisi, Georgia
Premier Journal of Neuroscience 2025;2:100006

Fig 1 | An independent relationship between controls and AD patients appears in the graph. The bar’s height or length represents the measured frequency value

The Role of Vitamin B12 Deficiency in Alzheimer’s Disease: A Geographical Case-Control Study on Hematological Parameters
Ambreen Ilyas1, Khadija Batool2,3, Hina Javed3, and Sana Shoukat3
1 School of Biological Sciences, University of the Punjab, Lahore, Pakistan
2 Department of Zoology, University of the Sialkot, Sialkot, Pakistan
3 Institute of Zoology, University of the Punjab, Lahore, Pakistan
Premier Journal of Neuroscience 2025;2:100005

Fig 4 | The construction of a standard CNN and human visual based on the observation of two-dimensional brain MRI scans demonstrates human visual formation Source: https://doi.org/10.1016/j.ejrad.2023.110934.

Revolutionizing Alzheimer’s Diagnostics: AI Tool Shows Superior Accuracy over Traditional Methods
Giorgi Svanishvili
Anatomical Researches and Skills Centre, Tbilisi, Georgia
Premier Journal of Neuroscience 2025;2:100004

Recent Advances in the Treatment of Diverse Patient Populations with Brain Cancer
Clark Jones
Pharmaceutical Scientist, Salt Lake City, Utah, USA
Premier Journal of Neuroscience 2024;1:100003

Fig 3 | Shows the pathway linking mitochondrial dysfunction to neuroinflammation and neuronal degeneration. Healthy mitochondria produce reactive oxygen species (ROS) at normal levels, but reduced mitophagy consequently results in the accumulation of damaged mitochondria with elevated ROS levels

Mitochondrial Dysfunction and Its Impact on Cellular Metabolism in Degenerative Diseases
Sher Zaman Safi
Department of Biochemistry, Faculty of Medicine, MAHSA University, Jenjarom, Selangor, Malaysia
Premier Journal of Neuroscience 2024;1:100002

Fig 2 | Schematic diagram illustrating the use of biomaterials in treating spinal cord injuries

Premier Journal of Neuroscience

About the Premier Journal of Neuroscience (PJN)

PJN Aims and Scope

Archive

Volume 5 – October – December 2025

Volume 4 – July – September 2025

Volume 3 – April – June 2025

Volume 2 – January – March 2025

Volume 1 – October-December 2024

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